中文摘要:
磁共振成像（MRI）是常规临床医学检测中一种重要的影像手段.钆（Gd）基金属有机框架（Gd-MOF）结合了稀土元素Gd特有的磁性和MOF独特的多孔框架结构，展现出优异的造影性能，是一类具有潜力的磁共振造影剂.综述了Gd-MOF造影剂的研究进展，并综合分析了影响其性能的多方面因素.
中文关键词: 钆(Gd) 金属有机框架材料(MOF) 造影剂 磁共振成像(MRI)
DOI：10.3969/J.ISSN.1000-5137.2019.06.005
基金项目: 国家自然科学基金（21601124；21701111）
Research progress of Gd-MOF magnetic resonance contrast agent
ZHOU Weixiu, LIN Jiaomin College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234, China
Abstract:
Magnetic resonance imaging(MRI) is an important imaging technology in routine clinical medicine.Gd-based metal organic framework material(Gd-MOF) combines the unique magnetism of rare earth element gadolinium(Gd) and the unique porous framework of MOF,showing excellent contrast performance.Gd-MOF represents a new kind of potential MRI contrast agent.In this paper,we summarized the recent research progress of Gd-MOF contrast agent.
Key words: gadolinium(Gd) metal organic framework(MOF) contrast agent magnetic resonance imaging(MRI)